ZYMOSANS

Z10 - Y4 - M3 - O1 - S1 - A1 - N1 - S1 has 22 points in Scrabble!

Z10 - Y3 - M4 - O1 - S1 - A1 - N2 - S1 has 23 points in Words with Friends!

Found in the OTCWL2014, SOWPODS, ENABLE, and WWF dictionaries