ZYZZYVA

- Any of various tropical American weevils of the genus Zyzzyva, often destructive to plants.

Z10 - Y4 - Z10 - Z10 - Y4 - V4 - A1 has 43 points in Scrabble!

Z10 - Y3 - Z10 - Z10 - Y3 - V5 - A1 has 42 points in Words with Friends!

Found in the OTCWL2014, SOWPODS, ENABLE, and WWF dictionaries