The highest scoring word in Words With Friends is AFFAIR with a total of 12 points.
Synonyms: event, incident, happening, occurrence, phenomenon, eventuality, episode, interlude, circumstance, set of circumstances, adventure, experience, case, matter, business, thing
Synonyms: relationship, love affair, romance, fling, flirtation, dalliance, liaison, entanglement, romantic entanglement, involvement, attachment, affair of the heart, intrigue