The highest scoring word in Words With Friends is BALEFUL with a total of 16 points.
Synonyms: menacing, threatening, unfriendly, hostile, antagonistic, evil, evil-intentioned, wicked, nasty, hate-filled, bitter, acrimonious, malevolent, malicious, malignant, malign, sinister, deadly, harmful, injurious, dangerous, noxious, virulent, pernicious, venomous, poisonous, vitriolic, vindictive