The highest scoring word in Words With Friends is CENTER with a total of 10 points.
Synonyms: foundation, basis, keystone, mainspring, mainstay, linchpin, bedrock, fundament, base, key, fundamental principle, main ingredient, central component, centrepiece, core, heart, centre, focus, crux, prop, backbone, anchor
Synonyms: establishment, centre, installation, place, depot, station, location, premises, site, post, base, camp