The highest scoring word in Words With Friends is CRUD with a total of 9 points.
Synonyms: mud, muck, mire, ooze, silt, alluvium, dirt, slime, slush, slurry
Synonyms: despicable person/people, rabble, riff-raff, refuse, garbage, trash, vermin, good-for-nothing(s), undesirable(s), the lowest of the low, the dregs of society