The highest scoring word in Words With Friends is DETEST with a total of 7 points.
Synonyms: abhor, hate, loathe, despise, abominate, execrate, regard with disgust, feel disgust for, feel repugnance towards, feel distaste for, shrink from, recoil from, shudder at, be unable to bear, be unable to abide, feel hostility to, feel aversion to, feel animosity to, find intolerable, dislike, disdain, have an aversion to