The highest scoring word in Words With Friends is EFFECT with a total of 15 points.
Synonyms: affect, influence, exert influence on, act on, work on, condition, touch, interact with, have an impact on, impact on, take hold of, attack, infect, strike, strike at, hit, result, consequence, upshot, outcome, out-turn, sequel, reaction, repercussions, reverberations, ramifications
Synonyms: belongings, possessions, personal possessions, personal effects, goods, worldly goods, chattels, goods and chattels, accoutrements, appurtenances
Synonyms: achieve, accomplish, carry out, succeed in, realize, attain, manage, bring off, carry off, carry through, execute, conduct, fix, engineer, perform, do, perpetrate, discharge, fulfil, complete, finish, consummate, conclude