The highest scoring word in Words With Friends is PURGES with a total of 12 points.
Synonyms: remove, get rid of, clear out, sweep out, expel, eject, exclude, evict, dismiss, sack, oust, axe, depose, eradicate, root out, weed out, scour
Synonyms: removal, expulsion, ejection, exclusion, eviction, clearance, clear-out, discharge, dismissal, sacking, ousting, deposition, eradication, rooting out, weeding out
Synonyms: laxative, enema, aperient, lenitive, cathartic, evacuant