The highest scoring word in Words With Friends is RUPTURE with a total of 12 points.
Synonyms: break, fracture, crack, break, fracture, crack, breach
Synonyms: sever, break, cut off, break off, breach, disrupt
Synonyms: breaking, breakage, cracking, cleavage, rupture, shattering, fragmentation, splintering, splitting, separation, bursting, disintegration
Synonyms: rift, estrangement, break-up, breach, split, severance, separation, parting, division, alienation