The highest scoring word in Words With Friends is TACKLING with a total of 19 points.
Synonyms: get to grips with, apply oneself to, address oneself to, address, set about, go about, get to work at, take forward, busy oneself with, set one's hand to, grapple with, approach, take on, attend to, see to, throw oneself into, try to solve, try to deal with, try to cope with, try to sort out
Synonyms: intercept, rugby-tackle, challenge, block, stop, attack