The highest scoring word in Words With Friends is LATTICE with a total of 11 points.
Synonyms: grid, latticework, fretwork, open framework, openwork, trellis, trelliswork, network, mesh, web, webbing, netting, net, tracery, interlacing, reticulation, reticulum, grate, grating, grille, grillwork, criss-cross, matrix