12 Letter Words That End in SIS

There are 114+ 12 letter words ending in SIS in our English dictionary. Every 12-letter SIS-ending word below is valid in the Scrabble (TWL and SOWPODS), Wordle, and Words With Friends dictionaries, sortable and ready for your next puzzle. You can also browse all words ending in SIS.

Popular 12-Letter Words Ending in SIS

angiogenesis 14
bilharziasis 26
coenesthesis 17
cryptobiosis 21
furunculosis 17
haematemesis 19
hyperostosis 20
hypnogenesis 21
karyokinesis 23
leukopoiesis 18
neurogenesis 13
orthotonesis 15

All 12-Letter Words Ending in SIS (68 words)

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How Common is SIS as an Ending 12 Letter word?

There are 114 12-letter words ending in SIS in English. The average Scrabble score here is 18.3.

Total Words
114
Avg Scrabble Score
18.3
Top Vowel Pairs
IA
AE

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12 Letter Words ending in SIS are often very useful for word games like Scrabble and Words with Friends. This list will help you to find the top scoring words to beat the opponent. Word Finder by WordTips gives you a list of words ordered by their word game points of your choice. You might also be interested in 12 Letter Words with SIS.

Are you playing Wordle? Try our New York Times Wordle Solver or use the Include and Exclude features on our 12 Letter Words page when playing Dordle, WordGuessr or any other Wordle-like games. They help you guess the answer faster by allowing you to input the good letters you already know and exclude the words containing your bad letter combinations.

Highest-Scoring 12-Letter SIS-Words in Scrabble

zygapophysis 35
bilharziasis 26
bilharziosis 26
hyperkinesis 24
parapophysis 24
karyokinesis 23

What is the highest scoring word in Scrabble that ends with SIS?

35 Points

The highest scoring word in Scrabble that ends with SIS is zygapophysis with a total of 35 points.

Z 10
Y 4
G 2
A 1
P 3
O 1
P 3
H 4
Y 4
S 1
I 1
S 1

FAQ 12 Letter Words That End in SIS

  • How many 12 letter words ending with SIS are in the English dictionary?

    There are 114 12-letter words in the English dictionary that end with SIS. The average Scrabble score across them is 18.3.

  • Are there any rare 12 letter words ending in SIS worth more in Scrabble?

    Yes. Uncommon 12-letter words like "bilharziasis", "zygapophysis", "bilharziosis", "toxocariasis" end with SIS and can score big thanks to their unusual letters. "zygapophysis" is worth 35 points in Scrabble before any bonus tiles.

  • What are the most common 12 letter words ending in SIS?

    Everyday 12-letter words ending in SIS include "angiogenesis", "bilharziasis", "coenesthesis", "cryptobiosis", "furunculosis".