Three-Letter Strategy
One of the key factors in games like Scrabble and Words With Friends is called rack balance. You want to keep the letters R-A-T-E-S in your rack because they are the most common letters and will help you form bingos more easily. Playing three-letter words, such as 3 letter words with Z or one of the 3 letter words with Q, is a great way to get "nonbingo" letters out of your rack with the ability to get better letters into it.
Some of the three letter words with Z include AZO, ZAP, ZIP, and ZEN, among others. There's a neat little word, too, in ZAX, which is an AX used to cut roofing slates. The X is the best hooking letter in the game, and if you can score it on a triple square of some sort, you can score between 62 and 70 points for a three-letter word! Some bingos don't score that well.
When it comes to 3 letter words ending in Q, there is only one: SUQ. There are only three 3 letter words ending in J: HAJ, RAJ, and TAJ. The J isn't quite as powerful as the X because it's tougher to hook, but these 3 letter words ending in J will help you score fairly well and maintain rack balance.
Of the 1,065 3 letter words, most are mundane, however. Even so, when the board is tight, three-letter words are sometimes your best play, particularly when using up possible space to keep your opponent from being able to play a bingo. Knowing all the 3 letter words with Z and that the list of 3 letter words ending in Q is just one word are two key skills in tight games.