reaching a high or the highest degree; very great

extreme cold

furthest from the centre or a given point

the extreme north-west of Scotland

either of two abstract things that are as different from each other as possible

we represented opposite extremes of college society—he a member of the Old Guard, I one of the radicals

the subject or predicate in a proposition, or the major or minor term in a syllogism (as contrasted with the middle term)