in the opposite direction from that in which a stream or river flows; nearer to the source

a lone motor cruiser rumbled upstream

watch your footing and always face upstream

the Jubilee River relieves flooding upstream of Windsor

two miles upstream from London

in or towards the part of a sequence of genetic material where transcription takes place earlier than at a given point

at a stage in the process of gas or oil extraction and production before the raw material is ready for refining

moving or situated in the opposite direction from that in which a stream or river flows

the upstream stretch of the river

situated in or towards the part of a sequence of genetic material where transcription takes place earlier than at a given point

relating to the stages in the process of gas or oil extraction and production before the raw material is ready for refining