(of a person) deprived of or lacking sexual qualities or attraction
they turned into folksy elder statesmen, sagacious but desexed
the desexed characters wander through an utterly neutered world
(of an animal) castrated or spayed
deprive (someone) of sexual qualities or attraction
my face looked pinched; unhappiness had desexed me
castrate or spay (an animal)
the clinic would encourage cat owners to desex their pets
the Royal Humane Society offered to desex the cat