feel or cause to feel in need of rest or sleep

soon the ascent grew steeper and he began to tire

the journey had tired her

the training tired us out

lose interest in; become bored with

the media will tire of publicizing every protest

the proof of a great story is that people never tire of retelling it

a rubber covering, typically inflated or surrounding an inflated inner tube, placed round a wheel to form a soft contact with the road

she had got a flat tyre while driving home

he was used to riding a mountain bike with wide tyres